I agree with a number of the posts above in that the time involved in switching hands is minimal because the bait is in the air anyway. I am a righty, but have learned to fly cast with both "hands". I fish traditional spinning gear and switch to right handed baitcasters without a problem. However, I also own two left handed baitcasters which I prefer for certain techniques. There are days when I switch between spinning gear, right handed BCs, and left handed BCS. Occasionally I reach for the reel handle on the wrong side, but much less often than you would expect. It really boils down to what is comfortable and works for you!